Pantoprazole induced a slow but sustained increase in 3rd compartment pH when given by both the IV and SC routes. Third compartment pH was recorded and plasma samples were taken for pharmacokinetic analysis. ![]() Alpacas received both IV and SC pantoprazole, with a minimum of 3 weeks between treatments. After recovery, alpacas received 1 mg/kg pantoprazole IV, q24h for 3 days or 2 mg/kg SC q24h for 3 days. To examine the pharmacokinetics of both IV and SC pantoprazole and to determine whether pantoprazole administration would increase 3rd compartment pH in alpacas.Īlpacas were fitted with a 3rd compartment cannula for measuring gastric pH. ![]() Despite frequent clinical use, information about the pharmacokinetics and efficacy of pantoprazole in camelids is not available.
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